* Papers with Sirius co-authors

* Anura S. Indulkar, Karl J. Box, Robert Taylor, Rebeca Ruiz, Lynne S. Taylor., pH-Dependent Liquid–Liquid Phase Separation of Highly Supersaturated Solutions of Weakly Basic Drugs. Mol. Pharmaceutics, 2015, 12 (7), 2365–2377

Fan, Y. Yang, M. Wang, Y. Li, Y.  Zhou, Y. Chen, X. Shan, L. Wei, J. Gao, C., Preformulation characterization and in vivo absorption in beagle dogs of JFD, a novel anti-obesity drug for oral delivery. Drug Development and Industrial Pharmacy, 2015, 41(5), 801-811

* Butcher, G. Comer, J. Avdeef, A., pKa-critical Interpretations of Solubility–pH Profiles: PG-300995 and NSC-639829 Case Studies. ADMET & DMPK, 2015, 3(2), 131-140

* D. Schönherr a, U. Wollatz a, D. Haznar-Garbacz a, U. Hanke a, K.J. Box b, R. Taylor b, R. Ruiz b, S. Beato c, D. Becker d, W. Weitschies a., Characterisation of selected active agents regarding pKa values, solubility concentrations and pH profiles by SiriusT3. Eur J Pharm Sci 2015

* Comer, J. Judge, S. Matthews, D. Towes, L. Falcone, B. Goodman, J. Dearden, J. The intrinsic aqueous solubility of indomethacin. ADMET & DMPK 2(1) (2014) 18-32.

Shoghi E, Fuguet E, Bosch E, Ràfols C. Solubility-pH Profiles of some Acidic, Basic and Amphoteric Drugs. Eur J Pharm Sci. 2013, 48, 291-300.

Schmidt, E.; Dooley, N.; Ford, S. J.; Elliott, M.; Halbert, G. W., Physicochemical investigation of the influence of saccharide-based parenteral formulation excipients on l-p-boronphenylalanine solubilisation for boron neutron capture therapy. J. Pharm. Sci. 2012, 101 (1), 223-23

* Völgyi, G.; Baka, E.; Box, K. J.; Comer, J. E.; Takács-Novák, K., Study of pH-dependent solubility of organic bases. Revisit of Henderson-Hasselbalch relationship. Anal Chim Acta 2010, 673 (1), 40-46.

* Box, K. Comer, J. E. Gravestock, T. Stuart, M. New ideas about the solubility of drugs. Chemistry and Biodiversity, 2009, 6, 1767-1788

* Box, K J. Comer, J E A. Using measured pKa, LogP and solubility to investigate supersaturation and predict BCS class. Current Drug Metabolism, 2008, 9(9), 869-878

* Study of equilibrium solubility measurement by saturation shake-flask method using hydrochlorothiazide as a model compound. Baka, E. Comer, J E A. Takács-Novák, K. J. Pharm. Biomed. Anal. 2008 46 335-341

Llinàs, A. Glen, R C. Goodman, J M. Solubility challenge: can you predict solubilities of 32 molecules using a database of 100 reliable measurements? J. Chem. Inf. Model. 2008, 48(7), 1289-1303

* Llinàs, A. Box, K J. Burley, J C. Glen, R C. Goodman, J M. A new method for the reproducible generation of polymorphs: two forms of sulindac with very different solubilities. J. Applied Crystallography, 2007, 40(2), 379-381

* Llinàs, A. Burley, J C. Box, K J. Glen, R C. Goodman, J M. Diclofenac Solubility: Independent Determination of the Intrinsic Solubility of Three Crystal Forms. J. Med. Chem.; 2007, 50 (5), 979-983

* Sköld, C. Winiwarter, S. Johan Wernevik, J. Bergström, F. Engström, L. Allen, R. Box, K. Comer, J. Mole, J. Hallberg, A. Lennernäs, H. Lundstedt, T. Ungell, A-L. Karlén, A. Presentation of a Structurally Diverse and Commercially Available Drug Data Set for Correlation and Benchmarking Studies. J. Med. Chem. 2006, 49(23), 6660-6671

* Box, K J. Völgyi, G. Baka, E. Stuart, M. Takács-Novák, K. Comer, J E A. Equilibrium vs. kinetic measurements of aqueous solubility, and the ability of compounds to supersaturate in solution - a validation study. J. Pharm. Sci. 2006, 95(6), 1298-1307

* Stuart, M. Box, K. Chasing equilibrium: measuring the intrinsic solubility of weak acids and bases. Anal. Chem. 2005 (77(4)) pp 983-990